If I had another SIGNIFICANT aspect
of my life...
The Big Bang Theory Season 2, Episode 3
Only my life.
Not all that SIGNIFICANT, I'm afraid.
Game of Thrones Season 3, Episode 3
But there's been
a SIGNIFICANT reduction
in the tumors.
Breaking Bad Season 2, Episode 10
it will represent a SIGNIFICANT rise
in your station.
Game of Thrones Season 5, Episode 7
with his SIGNIFICANT other.
The Big Bang Theory Season 7, Episode 5